Altered gut microbial metabolites in amnestic mild cognitive impairment and alzheimer's disease : signals in host-microbe interplay

• Main Authors: Wu, Li, Han, Yuqiu, Zheng, Zhipeng, Peng, Guoping, Liu, Ping, Yue, Siqing, Zhu, Shuai, Chen, Jun, Lv, Hanying, Shao, Lifang, Sheng, Yan, Wang, Yulan, Li, Liang, Li, Lanjuan, Wang, Baohong
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Medicine; Alzheimer’s Disease; Fecal Metabolomics
• Online Access: https://hdl.handle.net/10356/146413
• Institution: Nanyang Technological University

Intimate metabolic host-microbiome crosstalk regulates immune, metabolic, and neuronal response in health and disease, yet remains untapped for biomarkers or intervention for disease. Our recent study identified an altered microbiome in patients with pre-onset amnestic mild cognitive impairment (aMC...