A materials perspective on the design of damage-resilient bone implants through additive/advanced manufacturing

After more than 5 decades of research, the failure of bone implants is still poorly understood. The aging population makes it increasingly urgent to solve this issue. Among the reasons for failure, catastrophic brittle fracture can be directly related to the implant material and fabrication and dese...

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Main Authors:	Le Ferrand, Hortense, Athanasiou, Christos E.
Other Authors:	School of Materials Science and Engineering
Format:	Article
Language:	English
Published:	2021
Subjects:	Engineering::Materials Science::Medicine::Biomedical engineering Artificial Bones Implants
Online Access:	https://hdl.handle.net/10356/146702
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Institution:	Nanyang Technological University
Language:	English

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spelling	sg-ntu-dr.10356-1467022023-03-04T17:12:47Z A materials perspective on the design of damage-resilient bone implants through additive/advanced manufacturing Le Ferrand, Hortense Athanasiou, Christos E. School of Materials Science and Engineering School of Mechanical and Aerospace Engineering Brown university Engineering::Materials Science::Medicine::Biomedical engineering Artificial Bones Implants After more than 5 decades of research, the failure of bone implants is still poorly understood. The aging population makes it increasingly urgent to solve this issue. Among the reasons for failure, catastrophic brittle fracture can be directly related to the implant material and fabrication and deserves more attention. Indeed, clinically available implants do not sufficiently reproduce the hierarchical and heterogeneous microstructural organization of our natural bones, ultimately failing at replicating their mechanical strength and toughness. Nevertheless, recent advances in additive and advanced manufacturing have opened new horizons for the fabrication of biomimetic bone implants, challenging at the same time their characterization, testing, and modeling. This critical review covers selected recent achievements in bone implant research from a materials standpoint and aims at deciphering some of the most urgent issues in this multidisciplinary field. Nanyang Technological University Accepted version H. L. F. acknowledges financial support from Nanyang Technological University with the Start-Up grant M4082382.050. 2021-03-05T08:21:28Z 2021-03-05T08:21:28Z 2020 Journal Article Le Ferrand, H., & Athanasiou, C. E. (2020). A materials perspective on the design of damage-resilient bone implants through additive/advanced manufacturing. JOM, 72, 1195–1210. doi:10.1007/s11837-019-03999-3 1047-4838 https://hdl.handle.net/10356/146702 10.1007/s11837-019-03999-3 72 1195 1210 en JOM © 2020 The Minerals, Metals and Materials Society. All rights reserved. This paper was published by Springer in JOM and is made available with permission of The Minerals, Metals and Materials Society. The final publication is available at link.springer.com via https://doi.org/10.1007/s11837-019-03999-3 application/pdf
institution	Nanyang Technological University
building	NTU Library
continent	Asia
country	Singapore Singapore
content_provider	NTU Library
collection	DR-NTU
language	English
topic	Engineering::Materials Science::Medicine::Biomedical engineering Artificial Bones Implants
spellingShingle	Engineering::Materials Science::Medicine::Biomedical engineering Artificial Bones Implants Le Ferrand, Hortense Athanasiou, Christos E. A materials perspective on the design of damage-resilient bone implants through additive/advanced manufacturing
description	After more than 5 decades of research, the failure of bone implants is still poorly understood. The aging population makes it increasingly urgent to solve this issue. Among the reasons for failure, catastrophic brittle fracture can be directly related to the implant material and fabrication and deserves more attention. Indeed, clinically available implants do not sufficiently reproduce the hierarchical and heterogeneous microstructural organization of our natural bones, ultimately failing at replicating their mechanical strength and toughness. Nevertheless, recent advances in additive and advanced manufacturing have opened new horizons for the fabrication of biomimetic bone implants, challenging at the same time their characterization, testing, and modeling. This critical review covers selected recent achievements in bone implant research from a materials standpoint and aims at deciphering some of the most urgent issues in this multidisciplinary field.
author2	School of Materials Science and Engineering
author_facet	School of Materials Science and Engineering Le Ferrand, Hortense Athanasiou, Christos E.
format	Article
author	Le Ferrand, Hortense Athanasiou, Christos E.
author_sort	Le Ferrand, Hortense
title	A materials perspective on the design of damage-resilient bone implants through additive/advanced manufacturing
title_short	A materials perspective on the design of damage-resilient bone implants through additive/advanced manufacturing
title_full	A materials perspective on the design of damage-resilient bone implants through additive/advanced manufacturing
title_fullStr	A materials perspective on the design of damage-resilient bone implants through additive/advanced manufacturing
title_full_unstemmed	A materials perspective on the design of damage-resilient bone implants through additive/advanced manufacturing
title_sort	materials perspective on the design of damage-resilient bone implants through additive/advanced manufacturing
publishDate	2021
url	https://hdl.handle.net/10356/146702
_version_	1759858121415589888

A materials perspective on the design of damage-resilient bone implants through additive/advanced manufacturing

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