Optimizing the reduction potential of sulfonamides on PAMAM dendrimers

• Main Authors: Ghosh, Animesh, Tan, Nigel Chew Shun, Shi, Raymond R. S., Webster, Richard David, Steele, Terry W. J.
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Chemistry; Bis-sulfonamide; Cyclic Voltammetry
• Online Access: https://hdl.handle.net/10356/146712
• Institution: Nanyang Technological University

p-Toluenesulfonamide serves as an important functional group to protect alkyl amines. However, the electrochemical deprotection of sulfonamides requires relatively high reduction potentials (-2.4V vs SCE) that would interfere with other functional groups. Previous investigations suggest that method...