Determination of critical shear stress for maturation of human pluripotent stem cell-derived endothelial cells towards an arterial subtype

• Main Authors: Arora, Seep, Lam, Adele Jing Ying, Cheung, Christine, Yim, Evelyn K. F., Toh, Yi-Chin
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Medicine; Arterial‐venous Specification; Biophysical Cues
• Online Access: https://hdl.handle.net/10356/146741
• Institution: Nanyang Technological University

Human pluripotent stem cell-derived endothelial cells (hPSC-ECs) present an attractive alternative to primary EC sources for vascular grafting. However, there is a need to mature them towards either an arterial or venous subtype. A vital environmental factor involved in the arteriovenous specificati...