An NKX2-1GFP and TP63tdTomato dual fluorescent reporter for the investigation of human lung basal cell biology

• Main Authors: Goh, Kim Jee, Tan, Ee Kim, Lu, Hao, Roy, Sudipto, Dunn, Norris Ray
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Medicine; Cell Biology; Developmental Biology
• Online Access: https://hdl.handle.net/10356/147305
• Institution: Nanyang Technological University

Basal cells are multipotent stem cells responsible for the repair and regeneration of all the epithelial cell types present in the proximal lung. In mice, the elusive origins of basal cells and their contribution to lung development were recently revealed by high-resolution, lineage tracing studies....