Targeting telomerase in cancer cells using degrader-based platforms

Telomeres progressively shorten during each cell division as a result of the “end replication problem”. A hallmark of cancer is unrestricted cell proliferation, which correlates to the maintenance of telomere length through the activation of telomerase or telomerase-independent recombination mechani...

Full description

Saved in:
Bibliographic Details
Main Author: Lim, Natalie Bao Ying
Other Authors: Phan Anh Tuan
Format: Final Year Project
Language:English
Published: Nanyang Technological University 2021
Subjects:
Online Access:https://hdl.handle.net/10356/148039
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English