Fibrodysplasia ossificans progressiva : current concepts from bench to bedside

• Main Authors: Kaliya-Perumal, Arun-Kumar, Carney, Tom J., Ingham, Philip William
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Medicine; Bone Morphogenetic Protein; ACVR1
• Online Access: https://hdl.handle.net/10356/148375
• Institution: Nanyang Technological University

Heterotopic ossification (HO) is a disorder characterised by the formation of ectopic bone in soft tissue. Acquired HO typically occurs in response to trauma and is relatively common, yet its aetiology remains poorly understood. Genetic forms, by contrast, are very rare, but provide insights into th...