Altered interaction between alpha-synuclein and lipid modulates inclusion body formation
Alpha-Synuclein (αS) is strongly implicated in Parkinson’s disease (PD), characterized by the abnormal αS accumulation of cytoplasmic inclusions termed Lewy body (LB). Physiologically, αS exist predominantly as an unfolded monomer but forms α-helical structure upon lipid binding. The N-terminus segm...
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| Format: | Final Year Project |
| Language: | English |
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Nanyang Technological University
2021
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| Online Access: | https://hdl.handle.net/10356/148414 |
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| Institution: | Nanyang Technological University |
| Language: | English |