The effects of solid stress compression on mechano-sensitive targets and its role in breast cancer malignancy

• Main Author: Chiang, Rachel Hui Min
• Other Authors: Koh Cheng Gee
• Format: Final Year Project
• Language: English
• Published: Nanyang Technological University 2021
• Subjects: Science::Biological sciences::Molecular biology
• Online Access: https://hdl.handle.net/10356/148539
• Institution: Nanyang Technological University

As a tumour mass rapidly grows and expands, surrounding host tissues exert an applied solid stress on the tumour. Studies have found that solid stress compression on cancer cells favour an invasive and metastatic phenotype through the induction of molecular signalling cascade, genotypic and phenotyp...