A vascular-liver chip for sensitive detection of nutraceutical metabolites from human pluripotent stem cell derivatives

• المؤلفون الرئيسيون: Yu, Fang, Goh, Yeek Teck, Li, Huan, Chakrapani, Narmada Balakrishnan, Ni, Ming, Xu, Guo Lin, Hsieh, Tseng-Ming, Toh, Yi-Chin, Cheung, Christine, Iliescu, Ciprian, Yu, Hanry
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2021
• الموضوعات: Engineering::Bioengineering; Biomolecules; Blood Vessels; Microfluidic Devices
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/148758

Human pluripotent stem cell (hPSC) is a great resource for generating cell derivatives for drug efficiency testing. Metabolites of nutraceuticals can exert anti-inflammatory effects on blood vessels. However, the concentration of nutraceutical metabolites produced in hPSC-derived hepatocytes (hPSC-H...