Host DNA released by NETosis in neutrophils exposed to seasonal H1N1 and highly pathogenic H5N1 influenza viruses

• Main Authors: Chan, Louisa L. Y., Nicholls, John M., Peiris, Joseph Sriyal Malik, Lau, Yu Lung, Chan, Michael Chi Wai, Chan, Renee W. Y.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Medicine; Beta Interferon; Gamma Interferon Inducible Protein 10
• Online Access: https://hdl.handle.net/10356/149020
• Institution: Nanyang Technological University

Background: Neutrophil is of the most abundant number in human immune system. During acute influenza virus infection, neutrophils are already active in the early phase of inflammation - a time in which clinical biopsy or autopsy material is not readily available. However, the role of neutrophil in v...