Cancer-associated fibroblasts in tumor microenvironment - accomplices in tumor malignancy

• المؤلفون الرئيسيون: Liao, Zehuan, Tan, Zhen Wei, Zhu, Pengcheng, Tan, Nguan Soon
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2021
• الموضوعات: Science::Medicine; Cancer-associated Fibroblasts; Somatic Mutation Theory
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/149122

There is much cellular heterogeneity in the tumor microenvironment. The tumor epithelia and stromal cells co-evolve, and this reciprocal relationship dictates almost every step of cancer development and progression. Despite this, many anticancer therapies are designed around druggable features of tu...