A longitudinal study of serum brain-derived neurotrophic factor levels in first-episode schizophrenia

• Main Authors: Yee, Jie Yin, Lee, Tih-Shih, Lee, Jimmy Chee Keong
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::General; Psychiatry; Brain-derived Neurotrophic Factor; First-episode Psychosis
• Online Access: https://hdl.handle.net/10356/149212
• Institution: Nanyang Technological University

Biomarkers identified for psychosis might allow for early diagnosis, more accurate prognosis, and tailored individualized interventions. Brain-derived neurotrophic factor (BDNF) is suggested to be a likely candidate biomarker for the diagnosis and treatment evaluation in psychosis. The aims of present study were to examine the levels of serum BDNF in both patients with first-episode psychosis (FEP) and in healthy controls for a year, and to investigate the association between BDNF with symptom severity and remission status.