Flexible conducting polymer-based cellulose substrates for on-skin applications

Flexible electroactive cellulose-based substrates were successfully fabricated via electropolymerization either polypyrrole (PPy) or poly(3,4-ethylenedioxythiophene) (PEDOT) in the presence of sodium dodecyl sulfate (SDS) onto platinum-coated cellulose substrates. Results showed that the conductive...

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Main Authors: Fu, Xiaoxu, Wang, Jun Kit, Ramírez-Pérez, Ana C., Choong, Cleo, Lisak, Grzegorz
Other Authors: School of Civil and Environmental Engineering
Format: Article
Language:English
Published: 2021
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Online Access:https://hdl.handle.net/10356/149234
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1492342021-05-29T20:11:36Z Flexible conducting polymer-based cellulose substrates for on-skin applications Fu, Xiaoxu Wang, Jun Kit Ramírez-Pérez, Ana C. Choong, Cleo Lisak, Grzegorz School of Civil and Environmental Engineering School of Materials Science and Engineering Nanyang Environment and Water Research Institute Residues and Resource Reclamation Centre Engineering::Materials::Biomaterials Wound Dressing Electroactive Paper Flexible electroactive cellulose-based substrates were successfully fabricated via electropolymerization either polypyrrole (PPy) or poly(3,4-ethylenedioxythiophene) (PEDOT) in the presence of sodium dodecyl sulfate (SDS) onto platinum-coated cellulose substrates. Results showed that the conductive polymers were evenly deposited onto the platinum-coated cellulose substrates, respectively without compromising the submicro roughness topography of the substrate. In fact, nanoroughness feature was formed by the deposition of conductive polymers on the individual fibres of the cellulose paper, both of which are highly important in regulating cell adhesion, proliferation and migration. The various electroactive cellulose-based papers exhibited good mechanical and structural properties as well as good cytocompatibility by supporting the attachment and proliferation of immortalized human keratinocytes (HaCaT cells). In addition, copper (Cu2+) and the zinc (Zn2+) ions were proved to be successfully doped into these PPy- and PEDOT-cellulose substrates. The PEDOT resulted in the higher doping of Cu2+ and Zn2+ ions, which was confirmed by the ions release studies. Furthermore, the PEDOT-cellulose substrates exhibited significantly higher mechanical properties, better initial cell attachment and higher electrochemical capacitance as compared to PPy-cellulose substrates. Overall, the results suggested that the PEDOT-cellulose substrates could potentially be a better choice of smart skin dressings, integration interface between skin and artificial devices or implantable electronic materials. Economic Development Board (EDB) Nanyang Technological University Accepted version 2021-05-28T05:04:18Z 2021-05-28T05:04:18Z 2020 Journal Article Fu, X., Wang, J. K., Ramírez-Pérez, A. C., Choong, C. & Lisak, G. (2020). Flexible conducting polymer-based cellulose substrates for on-skin applications. Materials Science and Engineering: C, (108), 110392-. https://dx.doi.org/10.1016/j.msec.2019.110392 0928-4931 https://hdl.handle.net/10356/149234 10.1016/j.msec.2019.110392 108 110392 en Materials Science and Engineering: C © 2019 Elsevier B.V. All rights reserved. This paper was published in Materials Science and Engineering: C and is made available with permission of Elsevier B.V. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Engineering::Materials::Biomaterials
Wound Dressing
Electroactive Paper
spellingShingle Engineering::Materials::Biomaterials
Wound Dressing
Electroactive Paper
Fu, Xiaoxu
Wang, Jun Kit
Ramírez-Pérez, Ana C.
Choong, Cleo
Lisak, Grzegorz
Flexible conducting polymer-based cellulose substrates for on-skin applications
description Flexible electroactive cellulose-based substrates were successfully fabricated via electropolymerization either polypyrrole (PPy) or poly(3,4-ethylenedioxythiophene) (PEDOT) in the presence of sodium dodecyl sulfate (SDS) onto platinum-coated cellulose substrates. Results showed that the conductive polymers were evenly deposited onto the platinum-coated cellulose substrates, respectively without compromising the submicro roughness topography of the substrate. In fact, nanoroughness feature was formed by the deposition of conductive polymers on the individual fibres of the cellulose paper, both of which are highly important in regulating cell adhesion, proliferation and migration. The various electroactive cellulose-based papers exhibited good mechanical and structural properties as well as good cytocompatibility by supporting the attachment and proliferation of immortalized human keratinocytes (HaCaT cells). In addition, copper (Cu2+) and the zinc (Zn2+) ions were proved to be successfully doped into these PPy- and PEDOT-cellulose substrates. The PEDOT resulted in the higher doping of Cu2+ and Zn2+ ions, which was confirmed by the ions release studies. Furthermore, the PEDOT-cellulose substrates exhibited significantly higher mechanical properties, better initial cell attachment and higher electrochemical capacitance as compared to PPy-cellulose substrates. Overall, the results suggested that the PEDOT-cellulose substrates could potentially be a better choice of smart skin dressings, integration interface between skin and artificial devices or implantable electronic materials.
author2 School of Civil and Environmental Engineering
author_facet School of Civil and Environmental Engineering
Fu, Xiaoxu
Wang, Jun Kit
Ramírez-Pérez, Ana C.
Choong, Cleo
Lisak, Grzegorz
format Article
author Fu, Xiaoxu
Wang, Jun Kit
Ramírez-Pérez, Ana C.
Choong, Cleo
Lisak, Grzegorz
author_sort Fu, Xiaoxu
title Flexible conducting polymer-based cellulose substrates for on-skin applications
title_short Flexible conducting polymer-based cellulose substrates for on-skin applications
title_full Flexible conducting polymer-based cellulose substrates for on-skin applications
title_fullStr Flexible conducting polymer-based cellulose substrates for on-skin applications
title_full_unstemmed Flexible conducting polymer-based cellulose substrates for on-skin applications
title_sort flexible conducting polymer-based cellulose substrates for on-skin applications
publishDate 2021
url https://hdl.handle.net/10356/149234
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