Evolutionary approaches for predicting MHC peptide binding

• Main Author: Rajapakse, Menaka Priyadharasani
• Other Authors: Bertil Schmidt
• Format: Theses and Dissertations
• Language: English
• Published: 2009
• Subjects: DRNTU::Engineering::Computer science and engineering::Computer applications::Life and medical sciences
• Online Access: https://hdl.handle.net/10356/14955
• Institution: Nanyang Technological University

T cells of the immune system recognize short linear peptides, known as epitopes, derived from degradation of protein antigens and presented by major histocompatibility complex (MHC) molecules on the surface of antigen processing cells. Antigen presentations in MHC class I and II pathways are critica...