Evaluation of carrier size and surface morphology in carrier-based dry powder inhalation by surrogate modeling

• Main Authors: Farizhandi, Amir Abbas Kazemzadeh, Pacłaawski, Adam, Szlęk, Jakub, Mendyk, Aleksander, Shao, Yu-Hsuan, Lau, Raymond
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Engineering::Chemical engineering; Dry Powder Inhalation; Emitted Dose
• Online Access: https://hdl.handle.net/10356/150651
• Institution: Nanyang Technological University

In this work, design parameters of carrier-based dry powder inhalation were studied using surrogate modeling technique. The surrogate models constructed were then used to evaluate the key design parameters independently, which were otherwise difficult to determine based on experimental studies alone...