Photoacoustic resonance imaging

• Main Authors: Zhang, Ruochong, Gao, Fei, Feng, Xiaohua, Liu, Siyu, Ding, Ran, Zheng, Yuanjin
• Other Authors: School of Electrical and Electronic Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Engineering::Electrical and electronic engineering; Photoacoustics; Photoacoustic Resonance Effect
• Online Access: https://hdl.handle.net/10356/150844
• Institution: Nanyang Technological University

In this paper, a new imaging modality, named photoacoustic resonance imaging (PARI), is proposed and experimentally demonstrated. Being distinct from conventional single nanosecond laser pulse induced wideband PA signal, the proposed PARI method utilizes multiburst modulated laser source to induce PA resonant signal with enhanced signal strength and narrower bandwidth. Moreover, imaging contrast could be clearly improved than conventional single-pulse laser based PA imaging by selecting optimum modulation frequency of the laser source, which originates from physical properties of different materials beyond the optical absorption coefficient. Experimental validation on phantoms and ex vivo tissues have been performed to show the merits of the proposed PARI method with much improved image contrast.