A distinct parabrachial-to-lateral hypothalamus circuit for motivational suppression of feeding by nociception

• Main Authors: Phua, Siew Cheng, Tan, Yu Lin, Kok, Alison Maun Yeng, Senol, Esra, Chiam, Christine Jin Hui, Lee, Chun-Yao, Peng, Yanmin, Lim, Auriel Theodora Jacobea, Mohammad, Hasan, Lim, Jing-Xuan, Fu, Yu
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Medicine; Brain; Neurons
• Online Access: https://hdl.handle.net/10356/151045
• Institution: Nanyang Technological University

The motivation to eat is not only shaped by nutrition but also competed by external stimuli including pain. How the mouse hypothalamus, the feeding regulation center, integrates nociceptive inputs to modulate feeding is unclear. Within the key nociception relay center parabrachial nucleus (PBN), we...