Modulating conformational stability of human serum albumin and implications for surface passivation applications

• Main Authors: Park, Jae Hyeon, Ferhan, Abdul Rahim, Jackman, Joshua A., Cho, Nam-Joon
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Engineering::Materials; Protein Adsorption; Protein Aggregation
• Online Access: https://hdl.handle.net/10356/151369
• Institution: Nanyang Technological University

Human serum albumin (HSA) is one of the most abundant proteins in the human body and also used as a biomaterial coating. While there is significant interest in modifying the properties of solid supports to control HSA adsorption, there is an outstanding need to investigate whether modulating the con...