Ligand-activated progesterone receptor B activates transcription factor EB to promote autophagy in human breast cancer cells

Autophagy is an evolutionary conserved, self-eating process that targets cellular constituents for lysosomal degradation. Transcription factor EB (TFEB) is a master regulator of autophagy by inducing the expression of genes involved in autophagic and lysosomal degradation. In breast cancer, ligand-a...

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Bibliographic Details
Main Authors: Tan, Sijie, Bajalovic, Natasa, Wong, Esther S. P., Lin, Valerie Chun Ling
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/151472
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Institution: Nanyang Technological University
Language: English