Study of DNA condensation for applications in nucleosome interactions and gene delivery with novel peptide vehicles

• Main Author: Huang, Dandan
• Other Authors: James P. Tam
• Format: Theses and Dissertations
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Biological sciences::Human anatomy and physiology::Deoxyribonucleic acids
• Online Access: https://hdl.handle.net/10356/15165
• Institution: Nanyang Technological University

The basic idea of gene therapy is to replace abnormal genes with normal genes. To realize this replacement, carrier molecules called gene delivery vectors are needed. The shortcomings of viral gene delivery vectors have stimulated the development of nonviral vectors. In this work, a series of novel...