Fate mapping analysis reveals a novel murine dermal migratory Langerhans-like cell population

• Main Authors: Sheng, Jianpeng, Chen, Qi, Wu, Xiaoting, Dong, Yu Wen, Mayer, Johannes, Zhang, Junlei, Wang, Lin, Bai, Xueli, Liang, Tingbo, Sung, Yang Ho, Goh, Wilson Wen Bin, Ronchese, Franca, Ruedl, Christiane
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Medicine; Dermal Dendritic Cells; Langerhans Cells
• Online Access: https://hdl.handle.net/10356/151764
• Institution: Nanyang Technological University

Dendritic cells residing in the skin represent a large family of antigen-presenting cells, ranging from long-lived Langerhans cells (LC) in the epidermis to various distinct classical dendritic cell subsets in the dermis. Through genetic fate mapping analysis and single-cell RNA-sequencing, we have...