Near-infrared fluorescent macromolecular reporters for real-time imaging and urinalysis of cancer immunotherapy

• المؤلفون الرئيسيون: He, Shasha, Li, Jingchao, Lyu, Yan, Huang, Jiaguo, Pu, Kanyi
• مؤلفون آخرون: School of Chemical and Biomedical Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2021
• الموضوعات: Engineering::Bioengineering; Immunotherapy; Biological Imaging
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/151901
• المؤسسة: Nanyang Technological University

Real-time imaging of immunoactivation is imperative for cancer immunotherapy and drug discovery; however, most existing imaging agents possess "always-on" signals and thus have poor signal correlation with immune responses. Herein, renal-clearable near-infrared (NIR) fluorescent macromolec...