Streamlined MRM method transfer between instruments assisted with HRMS matching and retention-time prediction

• Main Authors: Yang, J. J., Han, Yuan, Mah, C. H., Wanjaya, Elvy Riani, Peng, Brenda Ang Sze, Xu, Tengfei, Liu, Min, Huan, T., Fang, Mingliang
• Other Authors: School of Civil and Environmental Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Engineering::Civil engineering; Multiple Reaction Monitoring Method Transfers; Liquid Chromatography-triple Quadrupole-tandem Mass Spectrometry
• Online Access: https://hdl.handle.net/10356/152046
• Institution: Nanyang Technological University

Multiple reaction monitoring (MRM) mode using liquid-chromatography tandem mass spectrometry (e.g., LC-QqQ-MS/MS) has been extensively employed in the small molecule analysis with trace levels in complex samples owing to its high sensitivity. However, most of the reported MRM methods are developed u...