An in vivo study of a rat fluid-percussion-induced traumatic brain injury model with [¹¹C]PBR28 and [¹⁸F]flumazenil PET imaging

• Main Authors: Ghosh, Krishna Kanta, Padmanabhan, Parasuraman, Yang, Chang-Tong, Wang, Zhimin, Palanivel, Mathangi, Ng, Kian Chye, Lu, Jia, Carlstedt-Duke, Jan, Halldin, Christer, Gulyás, Balázs
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Medicine; Traumatic Brain Injury; Lateral Fluid Percussion
• Online Access: https://hdl.handle.net/10356/152071
• Institution: Nanyang Technological University

Traumatic brain injury (TBI) modelled by lateral fluid percussion-induction (LFPI) in rats is a widely used experimental rodent model to explore and understand the underlying cellular and molecular alterations in the brain caused by TBI in humans. Current improvements in imaging with positron emissi...