Protease-antiprotease imbalance in bronchiectasis

• Main Authors: Oriano, Martina, Amati, Francesco, Gramegna, Andrea, De Soyza, Anthony, Mantero, Marco, Sibila, Oriol, Chotirmall, Sanjay Haresh, Voza, Antonio, Marchisio, Paola, Blasi, Francesco, Aliberti, Stefano
• 其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
• 格式: Article
• 語言: English
• 出版: 2021
• 主題: Science::Medicine; Bronchiectasis; Proteases
• 在線閱讀: https://hdl.handle.net/10356/152081

Airway inflammation plays a central role in bronchiectasis. Protease-antiprotease balance is crucial in bronchiectasis pathophysiology and increased presence of unopposed proteases activity may contribute to bronchiectasis onset and progression. Proteases' over-reactivity and antiprotease defic...