Protease-antiprotease imbalance in bronchiectasis

• المؤلفون الرئيسيون: Oriano, Martina, Amati, Francesco, Gramegna, Andrea, De Soyza, Anthony, Mantero, Marco, Sibila, Oriol, Chotirmall, Sanjay Haresh, Voza, Antonio, Marchisio, Paola, Blasi, Francesco, Aliberti, Stefano
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2021
• الموضوعات: Science::Medicine; Bronchiectasis; Proteases
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/152081

Airway inflammation plays a central role in bronchiectasis. Protease-antiprotease balance is crucial in bronchiectasis pathophysiology and increased presence of unopposed proteases activity may contribute to bronchiectasis onset and progression. Proteases' over-reactivity and antiprotease defic...