Crosstalk of immune signaling in regulating host effector-triggered immunity

• Main Author: Loh, Yu Thong
• Other Authors: Miao Yansong
• Format: Final Year Project
• Language: English
• Published: Nanyang Technological University 2021
• Subjects: Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/152349
• Institution: Nanyang Technological University

Plants possess two-tier defense system to protect themselves from pathogens. The first layer of immune response is PAMP-triggered immunity which is initiated by cell surface-localized pattern recognition receptors. Effector-triggered immunity is triggered when pathogenic effectors are perceived by plant resistance proteins. Plant resistance proteins contain a central nucleotide-binding and leucine-rich repeats and are usually termed as NLRs. The recognition of pathogen effectors by resistance proteins activates a more rapid and robust defense response, termed hypersensitive response. These two classes of immune system which involve different activation pathways were thought to have separate signaling components. However, recent studies revealed that they eventually converge into many similar downstream responses. In addition, increasing evidence suggests the crosstalk and interaction between PTI and ETI. Here, we discuss recent advances in our understanding of the crosstalk and cooperation between the two-branched of plant innate immunity.