Boron nitride nanosheets can induce water channels across lipid bilayers leading to lysosomal permeabilization

• Main Authors: Lucherelli, Matteo Andrea, Qian, Xuliang, Weston, Paula, Eredia, Matilde, Zhu, Wenpeng, Samorì, Paolo, Gao, Huajian, Bianco, Alberto, von dem Bussche, Annette
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Engineering::Nanotechnology; Science::Biological sciences::Biophysics; Engineering::Mathematics and analysis::Simulations; Science::Medicine::Biomedical engineering; Biomembranes; Cell Uptake; Lungs; Molecular Dynamics; Nanomaterials; White Graphene
• Online Access: https://hdl.handle.net/10356/152797
• Institution: Nanyang Technological University

While the interaction between 2D materials and cells is of key importance to the development of nanomedicines and safe applications of nanotechnology, still little is known about the biological interactions of many emerging 2D materials. Here, an investigation of how hexagonal boron nitride (hBN) in...