Multimodal approaches to study the isoform-specific role of FynT tyrosine kinase in association with tau pathology in alzheimer's disease and related tauopathies
Accumulating evidence has shown the involvement of Fyn tyrosine kinase in Alzheimer’s disease (AD), in particular in the formation of neurofibrillary tangles which is one of the hallmarks of AD. Our preliminary data showed that FynT isoform directly phosphorylated tau at Tyrosine18. The data also su...
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| Format: | Thesis-Master by Research |
| Language: | English |
| Published: |
Nanyang Technological University
2021
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| Online Access: | https://hdl.handle.net/10356/152838 |
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| Institution: | Nanyang Technological University |
| Language: | English |