P. falciparum RH5-Basigin interaction induces changes in the cytoskeleton of the host RBC

• Main Authors: Aniweh, Yaw, Gao, Xiaohong, Hao, Piliang, Meng, Wei, Lai, Soak-Kuan, Gunalan, Karthigayan, Chu, Trang T., Sinha, Ameya, Lescar, Julien, Chandramohanadas, Rajesh, Li, Hoi-Yeung, Sze, Siu Kwan, Preiser, Peter Rainer
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Biological sciences; Antibodies, Monoclonal; Calcium Signaling
• Online Access: https://hdl.handle.net/10356/153330
• Institution: Nanyang Technological University

The successful invasion of Plasmodium is an essential step in their life cycle. The parasite reticulocyte-binding protein homologues (RHs) and erythrocyte-binding like proteins are two families involved in the invasion leading to merozoite-red blood cell (RBC) junction formation. Ca2+ signaling has...