Comparative study on sustained release of metoclopramide salt from poly(D,L-lactide) and poly(D,L-lactide-co-glycolide) in-situ depots: formulation effects on drug release

• Main Author: Man, Shu Mei.
• Other Authors: Subramanian Venkatraman
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Engineering
• Online Access: http://hdl.handle.net/10356/15339
• Institution: Nanyang Technological University

In this research project, in situ depot drug delivery system was studied. This system is made up of biodegradable polymers, that are poly(d,l-lactide) (PDLLA) and poly(d,l-lactide-co-glycolide) (PLGA), dissolved in n-methyl-2-pyrrolidone (NMP). Metoclopramide monohydrochloride (metosalt) was used as...