Population-specific adaptation in malaria-endemic regions of Asia

• Main Authors: Gusareva, Elena S., Lorenzini, Paolo Alberto, Nurul Adilah Ramli, Ghosh, Amit Gourav, Kim, Hie Lim
• Other Authors: Asian School of the Environment
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Biological sciences; Social sciences::General; Malaria; Natural Selection; Adaptive Genes; Infectious Disease; Nervous System; Cerebral Malaria
• Online Access: https://hdl.handle.net/10356/153453
• Institution: Nanyang Technological University

Evolutionary mechanisms of adaptation to malaria are understudied in Asian endemic regions despite a high prevalence of malaria in the region. In our research, we performed genome-wide screening for footprints of natural selection against malaria by comparing eight Asian population groups from malar...