Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS)

The efficacy and tolerability of an antiretroviral regimen are important considerations for selection of HIV-1 infection maintenance therapy. Abacavir/lamivudine plus rilpivirine (ABC/3TC + RPV) has been shown in international studies to be effective and well-tolerated in virologically suppressed in...

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Main Authors:	Lim, Z. C., Hoo, G. S., Ang, J. H., Teng, C. B., Ang, L. W., Lee, C. C., Leo, Yee Sin, Law, Hwa Lin, Ng, Oon Tek, Wong, C. S.
Other Authors:	Lee Kong Chian School of Medicine (LKCMedicine)
Format:	Article
Language:	English
Published:	2021
Subjects:	Science::Medicine Maintenance Switch Therapy
Online Access:	https://hdl.handle.net/10356/153553
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Institution:	Nanyang Technological University
Language:	English

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spelling	sg-ntu-dr.10356-1535532023-03-05T16:48:40Z Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS) Lim, Z. C. Hoo, G. S. Ang, J. H. Teng, C. B. Ang, L. W. Lee, C. C. Leo, Yee Sin Law, Hwa Lin Ng, Oon Tek Wong, C. S. Lee Kong Chian School of Medicine (LKCMedicine) Science::Medicine Maintenance Switch Therapy The efficacy and tolerability of an antiretroviral regimen are important considerations for selection of HIV-1 infection maintenance therapy. Abacavir/lamivudine plus rilpivirine (ABC/3TC + RPV) has been shown in international studies to be effective and well-tolerated in virologically suppressed individuals. This study evaluated the effectiveness and safety of switching to ABC/3TC + RPV as maintenance therapy in virologically suppressed HIV-1 infected individuals in Singapore. Published version 2021-12-08T05:08:49Z 2021-12-08T05:08:49Z 2021 Journal Article Lim, Z. C., Hoo, G. S., Ang, J. H., Teng, C. B., Ang, L. W., Lee, C. C., Leo, Y. S., Law, H. L., Ng, O. T. & Wong, C. S. (2021). Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS). AIDS Research and Therapy, 18(1), 80-. https://dx.doi.org/10.1186/s12981-021-00402-7 1742-6405 https://hdl.handle.net/10356/153553 10.1186/s12981-021-00402-7 34724931 2-s2.0-85118584075 1 18 80 en AIDS Research and Therapy © The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativeco mmons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. application/pdf
institution	Nanyang Technological University
building	NTU Library
continent	Asia
country	Singapore Singapore
content_provider	NTU Library
collection	DR-NTU
language	English
topic	Science::Medicine Maintenance Switch Therapy
spellingShingle	Science::Medicine Maintenance Switch Therapy Lim, Z. C. Hoo, G. S. Ang, J. H. Teng, C. B. Ang, L. W. Lee, C. C. Leo, Yee Sin Law, Hwa Lin Ng, Oon Tek Wong, C. S. Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS)
description	The efficacy and tolerability of an antiretroviral regimen are important considerations for selection of HIV-1 infection maintenance therapy. Abacavir/lamivudine plus rilpivirine (ABC/3TC + RPV) has been shown in international studies to be effective and well-tolerated in virologically suppressed individuals. This study evaluated the effectiveness and safety of switching to ABC/3TC + RPV as maintenance therapy in virologically suppressed HIV-1 infected individuals in Singapore.
author2	Lee Kong Chian School of Medicine (LKCMedicine)
author_facet	Lee Kong Chian School of Medicine (LKCMedicine) Lim, Z. C. Hoo, G. S. Ang, J. H. Teng, C. B. Ang, L. W. Lee, C. C. Leo, Yee Sin Law, Hwa Lin Ng, Oon Tek Wong, C. S.
format	Article
author	Lim, Z. C. Hoo, G. S. Ang, J. H. Teng, C. B. Ang, L. W. Lee, C. C. Leo, Yee Sin Law, Hwa Lin Ng, Oon Tek Wong, C. S.
author_sort	Lim, Z. C.
title	Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS)
title_short	Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS)
title_full	Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS)
title_fullStr	Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS)
title_full_unstemmed	Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS)
title_sort	safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed hiv-1 individuals in singapore (seals)
publishDate	2021
url	https://hdl.handle.net/10356/153553
_version_	1759854455871766528

Safety and effectiveness of switching to abacavir/lamivudine plus rilpivirine for maintenance therapy in virologically suppressed HIV-1 individuals in Singapore (SEALS)

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