Pharyngeal microbial signatures are predictive of the risk of fungal pneumonia in hematologic patients

• Main Authors: Costantini, Claudio, Nunzi, Emilia, Spolzino, Angelica, Palmieri, Melissa, Renga, Giorgia, Zelante, Teresa, Englmaier, Lukas, Coufalikova, Katerina, Spáčil, Zdeněk, Borghi, Monica, Bellet, Marina M., Acerbi, Enzo, Puccetti, Matteo, Giovagnoli, Stefano, Spaccapelo, Roberta, Talesa, Vincenzo N., Lomurno, Giuseppe, Merli, Francesco, Facchini, Luca, Spadea, Antonio, Melillo, Lorella, Codeluppi, Katia, Marchesi, Francesco, Marchesini, Gessica, Valente, Daniela, Dragonetti, Giulia, Nadali, Gianpaolo, Pagano, Livio, Aversa, Franco, Romani, Luigina
• Other Authors: Singapore Centre for Environmental Life Sciences and Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Biological sciences; Hematological Malignancies; Airway Microbiome
• Online Access: https://hdl.handle.net/10356/153585
• Institution: Nanyang Technological University

The ability to predict invasive fungal infections (IFI) in patients with hematological malignancies is fundamental for successful therapy. Although gut dysbiosis is known to occur in hematological patients, whether airway dysbiosis also contributes to the risk of IFI has not been investigated. Nasal...