Inspection of intraocular lens with dual-side view optical coherence tomography

Intraocular lens (IOL) is widely used for cataract treatment. Its optical properties are crucial to obtain a good treatment efficacy and thus need to be evaluated and controlled. In this study, we propose a novel method based on optical coherence tomography (OCT) for noncontact and accurate in vitro...

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Main Authors: Wu, Qian, Wang, Xiwen, Liu, Linbo, Mo, Jianhua
Other Authors: School of Electrical and Electronic Engineering
Format: Article
Language:English
Published: 2021
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Online Access:https://hdl.handle.net/10356/153721
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1537212021-12-23T01:49:16Z Inspection of intraocular lens with dual-side view optical coherence tomography Wu, Qian Wang, Xiwen Liu, Linbo Mo, Jianhua School of Electrical and Electronic Engineering Engineering::Electrical and electronic engineering Optical Coherence Tomography Dual-Side View Intraocular lens (IOL) is widely used for cataract treatment. Its optical properties are crucial to obtain a good treatment efficacy and thus need to be evaluated and controlled. In this study, we propose a novel method based on optical coherence tomography (OCT) for noncontact and accurate in vitro measurement of thickness, refractive index and dioptric power of IOL implants. The OCT setup is specially designed to create two sampling optics, called dual-side view OCT (DSV-OCT), which allows for imaging IOL from the two opposite sides simultaneously in single OCT volume scanning. This can produce a three-dimensional surface contour without suffering image distortions due to the refraction of the curved surface. Then, the thickness and surface curvature can be easily computed from the surface contours. In addition, DSV-OCT is able to measure the refractive index. Three IOLs with different dioptric powers (5D, 20D and 28D) were chosen to evaluate this method. The results show that this method is capable to provide a comprehensive and accurate evaluation of IOLs from the aspects of thickness, refractive index and dioptric power, and hence can be potentially used as a quality assurance tool by IOL manufacturers. Ministry of Education (MOE) Ministry of Health (MOH) National Medical Research Council (NMRC) Published version This work was supported in part by the National Natural Science Foundation of China under Grant 81401451, in part by the Natural Science Foundation of the Jiangsu Province under Grant BK20140365, in part by the Postgraduate Research & Practice Innovation Program of Jiangsu Province under Grant 5832001320, in part by the Singapore Ministry of Health’s National Medical Research Council under its Open Fund Individual Research under Grant MOH-OFIRG19may-0009, and in part by the Ministry of Education Singapore under its Academic Research Fund under Grants 2018-T1-001-144 and T2EP30120-0001. 2021-12-23T01:49:15Z 2021-12-23T01:49:15Z 2021 Journal Article Wu, Q., Wang, X., Liu, L. & Mo, J. (2021). Inspection of intraocular lens with dual-side view optical coherence tomography. IEEE Photonics Journal, 13(3), 5800210-. https://dx.doi.org/10.1109/JPHOT.2021.3080498 1943-0655 https://hdl.handle.net/10356/153721 10.1109/JPHOT.2021.3080498 2-s2.0-85105847978 3 13 5800210 en MOH-OFIRG19may-0009 2018-T1-001-144 T2EP30120-0001 IEEE Photonics Journal © 2021 IEEE. This journal is 100% open access, which means that all content is freely available without charge to users or their institutions. All articles accepted after 12 June 2019 are published under a CC BY 4.0 license, and the author retains copyright. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, as long as proper attribution is given. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Engineering::Electrical and electronic engineering
Optical Coherence Tomography
Dual-Side View
spellingShingle Engineering::Electrical and electronic engineering
Optical Coherence Tomography
Dual-Side View
Wu, Qian
Wang, Xiwen
Liu, Linbo
Mo, Jianhua
Inspection of intraocular lens with dual-side view optical coherence tomography
description Intraocular lens (IOL) is widely used for cataract treatment. Its optical properties are crucial to obtain a good treatment efficacy and thus need to be evaluated and controlled. In this study, we propose a novel method based on optical coherence tomography (OCT) for noncontact and accurate in vitro measurement of thickness, refractive index and dioptric power of IOL implants. The OCT setup is specially designed to create two sampling optics, called dual-side view OCT (DSV-OCT), which allows for imaging IOL from the two opposite sides simultaneously in single OCT volume scanning. This can produce a three-dimensional surface contour without suffering image distortions due to the refraction of the curved surface. Then, the thickness and surface curvature can be easily computed from the surface contours. In addition, DSV-OCT is able to measure the refractive index. Three IOLs with different dioptric powers (5D, 20D and 28D) were chosen to evaluate this method. The results show that this method is capable to provide a comprehensive and accurate evaluation of IOLs from the aspects of thickness, refractive index and dioptric power, and hence can be potentially used as a quality assurance tool by IOL manufacturers.
author2 School of Electrical and Electronic Engineering
author_facet School of Electrical and Electronic Engineering
Wu, Qian
Wang, Xiwen
Liu, Linbo
Mo, Jianhua
format Article
author Wu, Qian
Wang, Xiwen
Liu, Linbo
Mo, Jianhua
author_sort Wu, Qian
title Inspection of intraocular lens with dual-side view optical coherence tomography
title_short Inspection of intraocular lens with dual-side view optical coherence tomography
title_full Inspection of intraocular lens with dual-side view optical coherence tomography
title_fullStr Inspection of intraocular lens with dual-side view optical coherence tomography
title_full_unstemmed Inspection of intraocular lens with dual-side view optical coherence tomography
title_sort inspection of intraocular lens with dual-side view optical coherence tomography
publishDate 2021
url https://hdl.handle.net/10356/153721
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