The repressor C protein, Pf4r, controls superinfection of Pseudomonas aeruginosa PAO1 by the Pf4 filamentous phage and regulates host gene expression

• Main Authors: Muhammad Hafiz Ismail, Michie, Katharine A., Goh, Yu Fen, Noorian, Parisa, Kjelleberg, Staffan, Duggin, Iain G., McDougald, Diane, Rice, Scott A.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Biological sciences::Microbiology; Bacteriophage; Gene Regulation
• Online Access: https://hdl.handle.net/10356/153753
• Institution: Nanyang Technological University

It has been shown that the filamentous phage, Pf4, plays an important role in biofilm development, stress tolerance, genetic variant formation and virulence in Pseudomonas aeruginosa PAO1. These behaviours are linked to the appearance of superinfective phage variants. Here, we have investigated the...