Rodent malaria erythrocyte preference assessment by an ex vivo tropism assay

• Main Authors: Leong, Yew Wai, Lee, Erica Qian Hui, Rénia, Laurent, Malleret, Benoit
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Erythrocyte Tropism; Reticulocyte
• Online Access: https://hdl.handle.net/10356/153908
• Institution: Nanyang Technological University

Circulating red blood cells consist of young erythrocytes (early and late reticulocytes) and mature erythrocytes (normocytes). The human malaria parasites, Plasmodium falciparum and P. vivax, have a preference to invade reticulocytes during blood-stage infection. Rodent malaria parasites that also p...