Ferroptosis induces membrane blebbing in placental trophoblasts

• Main Authors: Kajiwara, Kazuhiro, Beharier, Ofer, Chng, Choon-Peng, Goff, Julie P., Ouyang, Yingshi, St Croix, Claudette M., Huang, Changjin, Kagan, Valerian E., Hsia, K. Jimmy, Sadovsky, Yoel
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Chemical engineering; Ferroptosis; Blebs
• Online Access: https://hdl.handle.net/10356/154000
• Institution: Nanyang Technological University

Ferroptosis is a regulated, non-apoptotic form of cell death, characterized by hydroxy-peroxidation of discrete phospholipid hydroperoxides, particularly hydroperoxyl (Hp) forms of arachidonoyl- and adrenoyl-phosphatidylethanolamine, with a downstream cascade of oxidative damage to membrane lipids,...