AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody

• Main Authors: Merigliano, Chiara, Burla, Romina, La Torre, Mattia, Del Giudice, Simona, Teo, Hsiang Ling, Liew, Chong Wai, Chojnowski, Alexandre, Goh, Wah Ing, Olmos, Yolanda, Maccaroni, Klizia, Giubettini, Maria, Chiolo, Irene, Carlton, Jeremy G., Raimondo, Domenico, Vernì, Fiammetta, Stewart, Colin L., Rhodes, Daniela, Wright, Graham D., Burke, Brian E., Saggio, Isabella
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Biological sciences; Abscission; Machinery
• Online Access: https://hdl.handle.net/10356/154011
• Institution: Nanyang Technological University

To complete mitosis, the bridge that links the two daughter cells needs to be cleaved. This step is carried out by the endosomal sorting complex required for transport (ESCRT) machinery. AKTIP, a protein discovered to be associated with telomeres and the nuclear membrane in interphase cells, shares...