Genome wide study of tardive dyskinesia in schizophrenia

• Main Authors: Lim, Keane, Lam, Max, Zai, Clement, Tay, Jenny, Karlsson, Nina, Deshpande, Smita N., Thelma, B. K., Ozaki, Norio, Inada, Toshiya, Sim, Kang, Chong, Siow-Ann, Lencz, Todd, Liu, Jianjun, Lee, Jimmy
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Pharmacogenomics; Predictive Markers
• Online Access: https://hdl.handle.net/10356/154034
• Institution: Nanyang Technological University

Tardive dyskinesia (TD) is a severe condition characterized by repetitive involuntary movement of orofacial regions and extremities. Patients treated with antipsychotics typically present with TD symptomatology. Here, we conducted the largest GWAS of TD to date, by meta-analyzing samples of East-Asi...