Fixel-based analysis effectively identifies white matter tract degeneration in Huntington's disease

• المؤلفون الرئيسيون: Oh, Sher Li, Chen, Chiung-Mei, Wu, Yih-Ru, Hernandez, Maria Valdes, Tsai, Chih-Chien, Cheng, Jur-Shan, Chen, Yao-Liang, Wu, Yi-Ming, Lin, Yu-Chun, Wang, Jiun-Jie
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2022
• الموضوعات: Science::Medicine; Fixel-Based Analysis; Huntington’s Disease
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/154043
• المؤسسة: Nanyang Technological University

Microstructure damage in white matter might be linked to regional and global atrophy in Huntington's Disease (HD). We hypothesize that degeneration of subcortical regions, including the basal ganglia, is associated with damage of white matter tracts linking these affected regions. We aim to use...