Fixel-based analysis effectively identifies white matter tract degeneration in Huntington's disease

• Main Authors: Oh, Sher Li, Chen, Chiung-Mei, Wu, Yih-Ru, Hernandez, Maria Valdes, Tsai, Chih-Chien, Cheng, Jur-Shan, Chen, Yao-Liang, Wu, Yi-Ming, Lin, Yu-Chun, Wang, Jiun-Jie
• 其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
• 格式: Article
• 語言: English
• 出版: 2022
• 主題: Science::Medicine; Fixel-Based Analysis; Huntington’s Disease
• 在線閱讀: https://hdl.handle.net/10356/154043

Microstructure damage in white matter might be linked to regional and global atrophy in Huntington's Disease (HD). We hypothesize that degeneration of subcortical regions, including the basal ganglia, is associated with damage of white matter tracts linking these affected regions. We aim to use...