Functional characterization of the m⁶A-dependent translational modulator PfYTH.2 in the human malaria parasite

• Main Authors: Sinha, Ameya, Baumgarten, Sebastian, Distiller, Amy, McHugh, Emma, Chen, Patty, Singh, Meetali, Bryant, Jessica M., Liang, Jiaqi, Cecere, Germano, Dedon, Peter C., Preiser, Peter Rainer, Ralph, Stuart A., Scherf, Artur
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Biological sciences; Plasmodium Falciparum; m6A mRNA Methylation
• Online Access: https://hdl.handle.net/10356/154051
• Institution: Nanyang Technological University

Posttranscriptional regulation of gene expression is central to the development and replication of the malaria parasite, Plasmodium falciparum, within its human host. The timely coordination of RNA maturation, homeostasis, and protein synthesis relies on the recruitment of specific RNA-binding prote...