Commentary : reconciling hygiene and cleanliness : a new perspective from human microbiome

Human beings have co-evolved with the microorganisms in our environment for millions of years, and have developed into a symbiosis in a mutually beneficial/defensive way. Human beings have significant multifaceted relationships with the diverse microbial community. Apart from the important protectiv...

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Bibliographic Details
Main Authors: Yu, Boxuan, Yu, Bowei, Yu, Ligen
Other Authors: -
Format: Conference or Workshop Item
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/154604
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Institution: Nanyang Technological University
Language: English
Description
Summary:Human beings have co-evolved with the microorganisms in our environment for millions of years, and have developed into a symbiosis in a mutually beneficial/defensive way. Human beings have significant multifaceted relationships with the diverse microbial community. Apart from the important protective role of microbial community exposure in development of early immunity, millions of inimitable bacterial genes of the diverse microbial community are the indispensable source of essential nutrients like essential amino acids and essential fatty acids for human body. The essential nutrition from microbiome is harvested through xenophagy. As an immune effector, xenophagy will capture any microorganisms that touch the epithelial cells of our gastrointestinal tract, degrade them and turn them into nutrients for the use of our body.