Molecular entrapment in thermophilic ferritin for nanoformulation in photodynamic therapy

• Main Authors: Pasula, Rupali Reddy, Kuniyil, Ambili, Lim, Sierin
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Engineering::Chemical engineering; 3D Spheroids; Acridine Orange
• Online Access: https://hdl.handle.net/10356/154636
• Institution: Nanyang Technological University

Nanoformulation of therapeutic and diagnostic agents is beneficial as theyaccumulate at tumor sites due to enhanced permeability and retention effects.However, many in vitro studies performed on 2D cultures lack the realisticdimension of in vivo systems. In this work, a photosensitizer, acridine ora...