Photoinduced cross-coupling of aryl Iodides with alkenes
A protocol for photoinduced cross-coupling of aryl iodides having polar π-functional groups or elongated π-conjugation with alkenes has been developed. The radical cascade mechanism involving generation of aryl radicals via C-I bond homolysis of photoexcited aryl iodides and their subsequent additio...
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sg-ntu-dr.10356-1548302023-02-28T19:58:28Z Photoinduced cross-coupling of aryl Iodides with alkenes Liu, Yuliang Li, Haoyu Chiba, Shunsuke School of Physical and Mathematical Sciences Science::Chemistry Hydrocarbons Anions A protocol for photoinduced cross-coupling of aryl iodides having polar π-functional groups or elongated π-conjugation with alkenes has been developed. The radical cascade mechanism involving generation of aryl radicals via C-I bond homolysis of photoexcited aryl iodides and their subsequent addition to alkenes is proposed. The method enables iodide-selective cross-coupling over other halogen leaving groups with functional group compatibility on both arene and alkene motifs. Ministry of Education (MOE) Nanyang Technological University Accepted version This work was supported by funding from Nanyang Technological University (NTU) and the Singapore Ministry of Education (Academic Research Fund Tier 2: MOE2017-T2-1-064) (for S.C.). 2022-01-13T05:31:07Z 2022-01-13T05:31:07Z 2021 Journal Article Liu, Y., Li, H. & Chiba, S. (2021). Photoinduced cross-coupling of aryl Iodides with alkenes. Organic Letters, 23(2), 427-432. https://dx.doi.org/10.1021/acs.orglett.0c03935 1523-7060 https://hdl.handle.net/10356/154830 10.1021/acs.orglett.0c03935 33404249 2-s2.0-85099667380 2 23 427 432 en MOE2017-T2-1-064 Organic Letters This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.orglett.0c03935. application/pdf |
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English |
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Science::Chemistry Hydrocarbons Anions |
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Science::Chemistry Hydrocarbons Anions Liu, Yuliang Li, Haoyu Chiba, Shunsuke Photoinduced cross-coupling of aryl Iodides with alkenes |
| description |
A protocol for photoinduced cross-coupling of aryl iodides having polar π-functional groups or elongated π-conjugation with alkenes has been developed. The radical cascade mechanism involving generation of aryl radicals via C-I bond homolysis of photoexcited aryl iodides and their subsequent addition to alkenes is proposed. The method enables iodide-selective cross-coupling over other halogen leaving groups with functional group compatibility on both arene and alkene motifs. |
| author2 |
School of Physical and Mathematical Sciences |
| author_facet |
School of Physical and Mathematical Sciences Liu, Yuliang Li, Haoyu Chiba, Shunsuke |
| format |
Article |
| author |
Liu, Yuliang Li, Haoyu Chiba, Shunsuke |
| author_sort |
Liu, Yuliang |
| title |
Photoinduced cross-coupling of aryl Iodides with alkenes |
| title_short |
Photoinduced cross-coupling of aryl Iodides with alkenes |
| title_full |
Photoinduced cross-coupling of aryl Iodides with alkenes |
| title_fullStr |
Photoinduced cross-coupling of aryl Iodides with alkenes |
| title_full_unstemmed |
Photoinduced cross-coupling of aryl Iodides with alkenes |
| title_sort |
photoinduced cross-coupling of aryl iodides with alkenes |
| publishDate |
2022 |
| url |
https://hdl.handle.net/10356/154830 |
| _version_ |
1759856772335534080 |