Umpolung of donor-acceptor cyclopropanes : via N-heterocyclic carbene organic catalysis

• المؤلفون الرئيسيون: Nie, Guihua, Huang, Xuan, Wang, Zhongyao, Pan,Dingwu, Zhang, Junmin, Chi, Robin Yonggui
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2022
• الموضوعات: Science::Chemistry; Aldehydes; Catalysis
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/155078
• المؤسسة: Nanyang Technological University

A carbene-catalyzed formal umpolung of donor-acceptor (D-A) cyclopropanes is disclosed. The cyclopropane moiety is connected to an acetyl aldehyde that can be activated by a carbene catalyst. The initially electrophilic carbon attached to the donor group of the D-A cyclopropane aldehyde is inverted...