Continuous crystallization as a downstream processing step of pharmaceutical proteins : a review

Continuous crystallization has been proposed as the downstream processing step for the purification of pharmaceutical proteins aimed at alleviating the manufacturing bottleneck caused by the limitations of chromatography-based operations at high upstream production titers. Herein we reviewed the cur...

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Bibliographic Details
Main Authors: Pu, Siyu, Hadinoto, Kunn
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/155138
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Institution: Nanyang Technological University
Language: English