Graphene quantum dot-based nanocomposites for diagnosing cancer biomarker APE1 in living cells

• Main Authors: Zhang, Hao, Ba, Sai, Yang, Zhaoqi, Wang, Tianxiang, Lee, Jasmine Yiqin, Li, Tianhu, Shao, Fangwei
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Chemistry::Biochemistry; Nanocomposite; Cancer Diagnosis
• Online Access: https://hdl.handle.net/10356/155161
• Institution: Nanyang Technological University

As an essential DNA repair enzyme, apurinic/apyrimidinic endonuclease 1 (APE1) is overexpressed in most human cancers and is identified as a cancer diagnostic and predictive biomarker for cancer risk assessment, diagnosis, prognosis, and prediction of treatment efficacy. Despite its importance in ca...